Primatologist Davis (Dwayne Johnson) shares an unshakable bond with George, the extraordinarily intelligent silverback gorilla who has been in his care since he was young. When a greed-fueled corporationâ€™s genetic experiment goes awry, George and other animals across the country are mutated into aggressive supercreatures who destroy everything in their path. In this adrenaline-filled ride, Davis tries to find an antidote, not only to halt a global catastrophe but also to save the fearsome creature who was once his friend.
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